Benign prostatic hypertrophy. Benign Prostatic Hypertrophy
Conditions
Interventions
Intervention 1: Intervention group: The intervention group includes people 50 years old and older who receive pills Vitamin D with a dose of 50000 for 6 months.This drug should be taken every two week
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Man over 50 years old Asymptomatic or mild symptoms of benign prostatic hypertrophy based on the IPSS questionnaire. Patients with benign prostatic hypertrophy
Exclusion criteria
Exclusion criteria: BMI greater than 35 or pathologic weight loss (weight loss over 10% of body weight in the last 6 months) History of kidney stones, bladder and urinary tract Having prostate or bladder cancer or prostate surgery Acute or chronic prostatitis or frequent urinary tract infections• History of acute urinary retention or repeated catheters in the last three months Use of GnRH agonists, anti-androgens and any hormonal drug in the past six months, the use of herbal and non-herbal medicines to control and treat BPH The history of chronic diseases such as CVA, HTN, COPD, liver and kidney disease, and cancers .. Taking medications that affect vitamin D metabolism such as corticosteroids, phenytoin, phenobarbital, or regular use of vitamin D supplements over the past 3 months Taking diuretics such as Lasix and ... Alcohol consumption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prostate Volume. Timepoint: At the beginning of the study and six months later. Method of measurement: sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of clinical symptoms. Timepoint: At the beginning of the study, 3 months later, 6 months later. Method of measurement: IPSS questionnaire.;PSA. Timepoint: At the beginning of the study, 3 months later, 6 months later. Method of measurement: laboratory kit.;Vitamin D. Timepoint: At the beginning of the study, 3 months later, 6 months later. Method of measurement: blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbolfazl Zendedel
Tehran University of Medical Sciences
Outcome results
None listed