Vaginal Delivery. Spontaneous Vertex Delivery
Conditions
Interventions
Intervention 1: In the Intervention group, Isosorbide tablets (Isocor Tablet, 40 m, Aria Pharmacy) are used vaginally. Then 24 hours later, after re-establishing a bishop: 25 microgram vaginal misopr
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Pregnant mothers from 18 to 40 years old Bishop Score 6 and less with a range score of 0 to 13 Body mass in the first trimester of pregnancy in the normal range (26 - 19.8 kg . m2) 41 weeks pregnancy based on ultrasonography of the first trimester of pregnancy Singleton and cephalic pregnancy Having a normal fetal heart rate or proper biophysical in 48 hours before entering the study
Exclusion criteria
Exclusion criteria: Pregnant women with a history of headache Misoprostol contraindications Alcohol consumption Preeclampsia and eclampsia Uncontrolled diabetes Intrauterine growth restriction Polyhydramnios and oligohydramnios Placenta previa or any other factor that prevents the induction of labor Interaction medicine with Isosorbide
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time interval between administration of the first dose of Isosorbide until the cervix is fully ripened and dilated (hours). Timepoint: the time interval between administration of the first dose of Isosorbide until the cervix is fully ripened and dilated (hours). Method of measurement: ?Vaginal examinatin by Hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| The time interval between administration of the first dose of Isosorbide until delivery of the neonate. Timepoint: ?From administration of the first dose of Isosorbide until delivery of the neonate. Method of measurement: Hours.;The effect of Isosorbide on the Bishop score 24 hours after administration of Isosorbide. Timepoint: 24 hours after administration of Isosorbide To delivery. Method of measurement: Bishop Score Scale.;The effect of Isosorbide on the number of Misoprostol used during labor. Timepoint: 24 hours after intervention to delivery. Method of measurement: Number Of misoprostol suppository. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Shahnaz Barat
Babol University of Medical Sciences
Outcome results
None listed