Respiratory distress syndrome of newborn. Respiratory distress of newborn
Conditions
Interventions
Intervention 1: Intervention group: infant is separated from NCPAP and is allowed to breathe in the room air with FiO2 of 21% or with extra oxygen with FiO2 of 40% for 4 hours. Then, NCPAP with 5 cm H
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 30 Days
Inclusion criteria
Inclusion criteria: Gestational age equal to or less than 32 weeks and birth weight equal to or less than 1800 gr Starting NCPAP from first hours of birth to treat respiratory distress syndrome Treatment with NCPAP after weaning from positive pressure ventilation via endotracheal route The newborn should be under treatment with NCPAP for at least 24 hours 5th minute APGAR score above 4
Exclusion criteria
Exclusion criteria: Documented congenital heart anomalies (except for small atrial septal defect, patent foramen ovale, and patent ductus arteriosus (PDA)) definite or possible neuromuscular disease definite or possible syndrome need for surgery transfer to other hospital patients weighing less than 750 g at the time of randomization intraventricular hemorrhage (grade above 2) lung hypoplasia other life-threatening congenital anomalies thoracic or airway anomalies need for mechanical ventilation before NCPAP removal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Successful NCPAP weaning in the first attempt. Timepoint: After first attempt to NCPAP weaning. Method of measurement: Number of attempts. | — |
Secondary
| Measure | Time frame |
|---|---|
| The frequency of weaning. Timepoint: After each time of weaning from the device. Method of measurement: Document. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRoya Choopani
Esfahan University of Medical Sciences
Outcome results
None listed