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Evaluating the effect of injection of ketorolac or dexamethasone on pain and swelling following removal of third molar

Evaluating the effect of injection of ketorolac or dexamethasone into the ptrygomandibular space on pain and swelling following removal of third mandibular molar

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180910040981N1
Enrollment
60
Registered
2019-04-09
Start date
2018-10-07
Completion date
Unknown
Last updated
2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

impacted teeth. Impacted teeth

Interventions

Intervention 1: First intervention group:After anesthetic injection, 30 ml of Ketorolac is injected once before surgery. Intervention 2: Intervention group: After anesthetic injection, 8 ml of Dexame

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients enter the study after obtaining written consent. All patients are over 18 years of age The weight of all patients is below 100kg, Depending on the category of American Anesthesia Association in the ASA group one and two. Both groups require the treatment of one-sided low-grade third molars

Exclusion criteria

Exclusion criteria: Patients who have taken medication or sedation 24 hours before treatment Patients who have a history of allergy to dexamethasone or ketorolac Patients who receive more than 3 local anesthetic injections during the surgical procedure

Design outcomes

Primary

MeasureTime frame
Pain and discomfort severity. Timepoint: Immediately after surgery, 1, 3 and 6 hours later, and eventually on a daily basis for one week. Method of measurement: Visual Analog Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeed Hajmohamadi

Kerman University of Medical Sciences

Hajmohamadisaeed@yahoo.com+98 34 3211 8071

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026