Patients candidate for coronary artery bypass graft surgery. Unspecified complication of cardiac and vascular prosthetic device, implant and graft
Conditions
Interventions
Intervention 1: Intervention group: in group 1 melatonin tablet (Webber Naturals® Canada) (3 mg), the night before surgery (8 nights) and the morning of surgery (6 am) and the night of surgery(8 ni
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: Age 30 and older Candidate for elective coronary artery bypass graft under cardiopulmonary pumps Anesthesia class 1-3 Insensitivity to melatonin
Exclusion criteria
Exclusion criteria: Lack of informed consent Emergency Surgery Chronic or recent use of melatonin or hypnotic drugs Treated with barbiturates or anti psychotics History of liver or kidney disease or chronic pulmonary disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium incidence. Timepoint: From Start of study for 2 days after performing the CABG. Method of measurement: Based on CAM-ICU.;Severity of delirium. Timepoint: From Start of study for 2 days after performing the CABG. Method of measurement: Based on MDAS.;Mechanical ventilation duration. Timepoint: 6,8,10,12 ,24 hours after surgery. Method of measurement: Hour.;Duration of ICU staying. Timepoint: 2,3,4 days after surgery. Method of measurement: Day. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Javaherforoosh zadeh
Ahvaz University of Medical Sciences
Outcome results
None listed