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Effect of Dexamethasone and Ketrolac on postoperative pain

Effect of submucosal injection of Ketorolac versus Dexamethasone on postoperative pain after third molar surgery: A randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180906040960N1
Enrollment
60
Registered
2021-06-16
Start date
2018-11-11
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain intensity and number of analgesics used by patients after impacted mandibular third molar surgery.

Interventions

Intervention 1: Intervention group 1: "group K" received 1ml ketorolac 30 mg. Intervention 2: Intervention group 2: "group D" received 1ml dexamethasone 4mg. Intervention 3: Control group: "Group C" r

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients must be over 16 years old. Patients who according to the category ASA are in group 1or 2. People who have not taken any painkillers a week before surgery. The patient should not have any infection or pain or other medical problems in the week before surgery. All the patients have at least one impacted mandibular third molar detected by a panoramic radiograph. The impacted teeth categorized as class II relationship, position ‘B’ angulation.

Exclusion criteria

Exclusion criteria: Patient who has not any gastrointestinal diseases. Impacted tooth has no symptom. Procedure prolonged more than 30. The patient is pregnant or breastfeeding. The patient has a physical or mental disability. Patient with a history of allergies or contraindications for nonsteroidal anti-inflammatory drugs. During the study period, the patient develops a complication that interferes with his treatment. The patient is taking medication due to a disease.

Design outcomes

Primary

MeasureTime frame
Pain intensity in patients in Ketorolac group. Timepoint: Measurement of patients' pain intensity before surgery and after surgery with an interval of one hour until 12 hours after surgery. Method of measurement: VAS.;Pain intensity in patients in Dexamethasone group. Timepoint: Measurement of patients' pain intensity before surgery and after surgery with an interval of one hour until 12 hours after surgery. Method of measurement: VAS.;Pain intensity of group patients in control. Timepoint: Measurement of patients' pain intensity before surgery and after surgery with an interval of one hour until 12 hours after surgery. Method of measurement: VAS.;Number of Analgesics in the Ketorolac group. Timepoint: Immediately after surgery up to 72 hours after surgery. Method of measurement: Number of pills by day.;Number of Analgesics in Dexamethasone group. Timepoint: Immediately after surgery up to 72 hours after surgery. Method of measurement: Number of pills by day.;Number of analgesics used in the control group. Timepoint: Immediately after surgery up to 72 hours after surgery. Method of measurement: Number of pills by day.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDariush Hasheminia

Esfahan University of Medical Sciences

farhad73mardani@gmail.com+98 31 3792 5523

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026