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Comparison of the effect of local and intramuscular injection of dexamethasone on side effects following surgical removal of impacted mandibular third molars

Comparison of the effect of local and intramuscular injection of dexamethasone on the amount of mouth opening, pain and swelling following surgical removal of impacted mandibular third molars

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180905040955N1
Enrollment
25
Registered
2019-05-31
Start date
2018-11-22
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain,edema and trismus after impacted lower third molar surgery.

Interventions

Intervention 1: Intervention group: In this group, local dexamethasone injection will perform then local anesthesia will perform. after surgical incision and bone removal third molar will extract. T

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: difficulty of surgical process on both side of surgery should be equal patient's consent for surgery. patients should have same impacted lower third molars on both side according to pell and gregory category.

Exclusion criteria

Exclusion criteria: use of drugs that interact with treatment plan systemic diseases smoking pericronitis, infection or pain on the site of surgery contraindication for use of corticostreoids recent history of using NSAIDs patients with GI problems allergy to NSAIDs pregnancy

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 1st day and 3rd day and 7th day after surgery. Method of measurement: visual analogue scale.;Edema. Timepoint: 1st day and 3rd day and 7th day after surgery. Method of measurement: flexible ruler.;Mouth opening. Timepoint: 1st day and 3rd day and 7th day after surgery. Method of measurement: flexible ruler.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaied Nezafati

Tabriz University of Medical Sciences

hamidreza.mohammadi.pajuhan@gmail.com+98 44 3344 4598

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026