Comparison of Primary Needling and Medical Management after Ahmed Glaucoma Valve Insertion in Controlling Post-Operative Elevated Intraocular Pressure: a Randomised Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180902040928N2

Enrollment

Registered

2020-06-22

Start date

2020-04-27

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma. Glaucoma

Interventions

Intervention 1: Intervention group: included patients undergoing conventional Ahmed Glaucoma Valve (AGV) with Beleb needling. Intervention 2: Control group: included patients undergoing conventional A

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All Patients with IOPs more than target pressure for which glaucoma drainage implant (GDI) surgery is planned are enrolled in the clinical trial with no age limit.

Exclusion criteria

Exclusion criteria: Congenital glaucoma No light perception at baseline History of ocular surface infection in recent two weeks Pregnancy Breast feeding Lack of healthy conjunctiva for AGV insertion

Design outcomes

Primary

Measure	Time frame
Intraocular pressure. Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Goldman applanation tonometry.	—

Secondary

Measure	Time frame
Number of eyes requiring medications. Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Quantitative.;Number of medications. Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Quantitative.;Number of Beleb needling. Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Quantitative.;Best corrected visual acuity (BCVA). Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Tumbling E-chart.;Complications. Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Qualitative.	—

Measure

Time frame

Number of eyes requiring medications. Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Quantitative.;Number of medications. Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Quantitative.;Number of Beleb needling. Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Quantitative.;Best corrected visual acuity (BCVA). Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Tumbling E-chart.;Complications. Timepoint: First day, first week, month 1 every week, month 3, 6, 9 and 12 after the surgery. Method of measurement: Qualitative.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Yadegari

Basir eye health research center

fateme.vafaei86@gmail.com+98 21 6694 0404

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026