Comparison of the effects of Alendronate and Vitamin D administration on lumbosacral vertebral fusion

Comparison of the effects of Alendronate and Vitamin D administration on lumbosacral vertebral fusion in patients undergoing posterior spinal cord fusion

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180826040869N2

Enrollment

Registered

2020-05-04

Start date

2019-06-05

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal fusion. Osseous stenosis of neural canal

Interventions

Intervention 1: Intervention group 1: In the Alendronate group, 70 mg of oral Alendronate was given as treatment every 6 weeks for 6 months. Intervention 2: Intervention group 2: Patients received 50,

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Lumbar discopathy patients spinal canal stenosis lumbar Listis Cr <1.2 age between 20 and 65 years

Exclusion criteria

Exclusion criteria: Patients with traumatic lesions Neoplastic lesions Infectious lesions Surgical history Disabling underlying problems and rheumatic diseases Patients with a history of osteoarthritis and vitamin D deficiency less than 10 units Patients with renal insufficiency and GFR below 40

Design outcomes

Primary

Measure	Time frame
Percentage of people with no fusion. Timepoint: Patients will be re-examined and fusion of the vertebrae one month, three months, and six months after surgery. Method of measurement: Check CT scan stereotype.;Percentage of people with low pain scores. Timepoint: Patients will be re-examined for pain severity one month, three months, and six months after surgery. Method of measurement: From the visual analog scale vas (visual Analog Scale).	—

Measure

Time frame

Percentage of people with no fusion. Timepoint: Patients will be re-examined and fusion of the vertebrae one month, three months, and six months after surgery. Method of measurement: Check CT scan stereotype.;Percentage of people with low pain scores. Timepoint: Patients will be re-examined for pain severity one month, three months, and six months after surgery. Method of measurement: From the visual analog scale vas (visual Analog Scale).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMisagh Shafizad

Mazandaran University of Medical Sciences

mi.shafizad@gmail.com+98 11 3336 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026