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Evaluation the efficacy of orthodontic adhesive containing titanium dioxide and chitosan nano-particles in fixed orthodontic patients

Evaluation the effect of orthodontic adhesive containing titanium dioxide and chitosan nano-particles on mineral content and streptococcus mutans population in fixed orthodontic patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180826040866N1
Enrollment
50
Registered
2018-11-15
Start date
2019-02-20
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Demineralization of tooth enamel.

Interventions

Intervention 1: Intervention group: In this group, for bonding brackets the composite (Transbond XT, 3M, USA), which adds 5% by weight of titanium dioxide nanoparticles and 5% by weight of nanochitosa

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
13 Years to 18 Years

Inclusion criteria

Inclusion criteria: Orthodontic patients aged between 13-18 years undergoing fixed orthodontic treatment Healthy gum Upper second premolars and upper lateral incisors of the participants to be free of macroscopic enamel cracks, caries, or enamel hypoplasia.

Exclusion criteria

Exclusion criteria: Patients taking medications that cause xerostomia. Systemic disease or active periodontal disease Active caries on at least one tooth

Design outcomes

Primary

MeasureTime frame
Population of Sterptococcus Mutans. Timepoint: 24 hours, 2 months and 6 months after placing brackets. Method of measurement: Real-time polymerase chain reaction.

Secondary

MeasureTime frame
?Determination of mineral context of enamel. Timepoint: 24 hours, 2 months and 6 months after placing brackets. Method of measurement: Quantitative laser fluorescence technique.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFahimeh Farzanegan

Mashhad University of Medical Sciences

farzaneganf@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026