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The efficacy of Eplerenon drug in patient with Acute CSCR (Central SerousChorioretinopathy)

The efficacy of Eplerenon drug in patient with Acute CSCR (Central SerousChorioretinopathy)

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180825040860N1
Enrollment
40
Registered
2019-09-28
Start date
2019-09-23
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Serous Chorioretinopathy. Central serous chorioretinopathy

Interventions

Intervention 1: Intervention group: for patients of treatment group, Eplerenon was initiated. in the first week, 25 mg daily and for the three next weeks, 50 mg daily was administered. Intervention 2:

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Acute onset of disease (less than 3 months) without history of previous treatments including treatment with drugs, PDT, Photocuagulation LASER absence of any pathology and impaired vision in other eye absence of ophthalmic eye pathology such as Glaucoma, Retinal disease and uveitis not taking corticostroids agents normal kidney lab tests for "treatment" group having consent to participating in study

Exclusion criteria

Exclusion criteria: does not having Consent to participating in study Younger than 18 years old suffering from any ocular or kidney disease

Design outcomes

Primary

MeasureTime frame
Best Corrected visual aquity. Timepoint: before and one month after initiation of intervention. Method of measurement: snellen chart.;Central macular thickness. Timepoint: before and one month after initiation of intervention. Method of measurement: optical coherence topogrphy.;Macular volume. Timepoint: before and one month after initiation of intervention. Method of measurement: optical coherence topogrphy.;Choroidal thickness. Timepoint: before and one month after initiation of intervention. Method of measurement: optical coherence topogrphy.

Secondary

MeasureTime frame
Adverse effects of eplerenon. Timepoint: during intervention. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Tohidi

Esfahan University of Medical Sciences

dr.tohidi1387@yahoo.com+98 31 3445 2031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026