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The effects of resistance training on serum levels of hs-CTnI, NT-proBNP, GDF-15, and cardiac damage markers

The effects of resistance training on serum levels of hs-CTnI, NT-proBNP, GDF-15, and cardiac damage markers in healthy and diabetic elderly men

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180819040831N1
Enrollment
24
Registered
2018-09-03
Start date
2018-08-31
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effects of resistance training on serum levels of hs-CTnI, NT-proBNP, GDF-15 and cardiac injury markers in healthy and diabetic elderly men.

Interventions

Intervention group: Perform exercises for 8 weeks and 3 sessions per week. The exercise protocol for these people includes 5 minutes of warming (jumping or cycling), the main body of the training and

Sponsors

Guilan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
65 Years to 78 Years

Inclusion criteria

Inclusion criteria: Men aged between 65 and 78 years old

Exclusion criteria

Exclusion criteria: Have cardiovascular disease Use tobacco and alcohol Have been regularly involved in sports activities in the last 1 year

Design outcomes

Primary

MeasureTime frame
Hs-CTnI. Timepoint: Before and after exercise. Method of measurement: Human cardiac troponin I(hs-CTnI) (Diasorin Kit)high sensitive.;NT-proBNP. Timepoint: Before and after exercise. Method of measurement: Human N-terminal pro-brain natriuretic peptide,NT-proBNP, ELISA kit.;Isophorm growth differentiation factor 15. Timepoint: Before and after exercise. Method of measurement: Human growth differentiation factor 15, ELISA kit.;Creatine kinase type MB. Timepoint: Before and after exercise. Method of measurement: creatine kinase-myocardial band, kit Pars test.;Total creatine kinase level. Timepoint: Before and after exercise. Method of measurement: creatine kinase, kit Pars test.;Lactate dehydrogenase. Timepoint: Before and after exercise. Method of measurement: Using the Pars kit, test lactate dehydrogenase.

Secondary

MeasureTime frame
Reducing the risk of cardiovascular disease. Timepoint: The beginning and end of the exercise. Method of measurement: Blood collection using laboratory kits.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahman Mirzaei

Guilan University

e.rangraz56@gmail.com+98 26 3736 0308

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026