Condition 1: Premature ovarian failure. Condition 2: Poor ovarian responders. Female infertility associated with anovulation Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: First intervention group(premature ovarian failure): At first test serum AMH, estradiol (E2), FSH and LH a few days before intervention. In intervention day PRP process with Rooyagen k
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 42 Years
Inclusion criteria
Inclusion criteria: Patient with premature ovarian failure patient with poor ovarian reserve (AFC<5-7 and AMH<0.5-1.1 ng/ml)
Exclusion criteria
Exclusion criteria: IgA deficiency Ovarian failure secondary to sex chromosome abnormality Pelvic adhesion scondary to abdominal surgery Chronic pelvic pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FSH level. Timepoint: Some days before injection and 1, 2 months after injection. Method of measurement: Check in labratory.;AMH level. Timepoint: Some days before injection and 1, 2 months after injection. Method of measurement: Check in labratory.;Estradiol level. Timepoint: Some days before injection and 1, 2 months after injection. Method of measurement: Check in labratory.;LH level. Timepoint: Some days before injection and 1, 2 months after injection. Method of measurement: Check in labratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Chemical pregnancy. Timepoint: 1 year after the first PRP injection. Method of measurement: Laboratory measurement of Beta hCG.;Clinical pregnancy. Timepoint: 5 weeks after positive Beta hCG. Method of measurement: Observation of fetal heart rate in sonography.;Live birth. Timepoint: 36 weeks after positive Beta hCG. Method of measurement: Delivery of live-born baby. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Lida Saeed
Yazd University of Medical Sciences
Outcome results
None listed