Type 2 Diabetes. Diabetes mellitus due to underlying condition
Conditions
Interventions
Intervention 1: Intervention group: 20 g/day wheat germ for 12 weeks. Wheat germ will manufactured by Narin Company (Isfahan, Iran). Intervention 2: Control group: 20 g/day placebo (bread powder) for
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Willingness to participation in the study Diagnosis of diabetes in the last 5 years Body mass index <35
Exclusion criteria
Exclusion criteria: Using insulin or oral agents inducing insulin secretion Smoking Pregnancy and lactation Using anti-psychotic drugs Taking antioxidant supplements within the past 3 months before the intervention Having a history of cancer, cardiovascular disease, renal, hepatic and thyroid disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood sugar. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Colorimetric.;Hemoglobin A1C. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: High-performance liquid chromatography.;Insulin. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Enzyme-linked immunosorbent assay (ELISA). | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Digital scale.;Waist Circumference. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: non-stretching tape measure.;Systolic blood pressure. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Sphygmomonometer.;Diastolic blood pressure. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Sphygmomonometer.;Total cholesterol. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Enzymatic method.;Triglyceride. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Enzymatic method.;Low density lipoprotein-cholestrol. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Enzymatic method.;High density lipoprotein-cholestrol. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Enzymatic method.;Brain derived neurotrophic factor. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: enzyme-linked immunosorbent assay (ELISA).;Malodialdehyde. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: enzyme-linked immunosorbent assay (ELISA).;Total antioxidant capacity. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: enzyme-linked immunosorbent assay (ELISA).;Depression score. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Depression Anxiety and Stress Scales (DASS-21).;Anxiety score. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Depression Anxiety and Stress Scales (DASS-21).;Stress score. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Depression Anxiety and Stress Scales (DASS-21).;Appetite. Timepoint: Before intervention and | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Amani
Esfahan University of Medical Sciences
Outcome results
None listed