Comparison of anesthetic efficacy of 2% lidocaine and 3% mepivacaine in premolars of maxilla with irreversible pulpitis

Comparison of anesthetic efficacy of 2% lidocaine with 1/100000 epinephrine and 3% mepivacaine in premolars of maxilla with irreversible pulpitis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180818040824N1

Enrollment

Registered

2018-10-30

Start date

2018-02-20

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthetizing the teeth.

Interventions

Intervention 1: Intervention group: Infusion of buccal infiltration one cartridge (1.8 ml) local 3% mepivacaine anesthetic solution, manufactured by the Canadian Novocol. Intervention 2: Control group

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The presence of maxillary premolars with irreversible pulpitis People aged 18 to 65

Exclusion criteria

Exclusion criteria: We have to inject another anesthetic solution. Allergies to local anesthetics and sulfites Pregnant women Taking any medication 6 hours before referral Having Systemic Disease The widening of periodontal ligament space The presence of a periapical radiolucency

Design outcomes

Primary

Measure	Time frame
Patient pain during treatment. Timepoint: While providing access cavity. Method of measurement: Visual analogue scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeide Jafari

Yasouj University of Medical Sciences

saeide.jafari73@gmail.com+98 74 3333 5199

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026