Skip to content

Double blinded clinical trial

Comparison of effect of levofloxacine +doxycycline with rifampin + doxycycline in treatment and relapse of brucellosis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180817040819N1
Enrollment
280
Registered
2019-02-11
Start date
2018-12-22
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brucellosis disease. Brucellosis due to Brucella melitensis

Interventions

Intervention 1: Intervention group: patients with brucellosis who is diagnosed by clinical finding and lab data . patients with compatible sign and symptom
if have a wright test equal or more than 1/160 is allocated in case group. This group receive levofloxacine 750 mg daily and doxycycline 100 mg twice daily . 1 and 2 month after treatment CBC, ESR,CRP
if have a wright test equal or more than 1/160 is allocated in case group and this group will be treated by doxtcycline and rifampine for 2 month. Dosage of doxycycline is 100 mg BD and rifampine

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients older than 18 years with brucellosis

Exclusion criteria

Exclusion criteria: pregnancy history of sensitivity to drug meningitis endocarditis

Design outcomes

Primary

MeasureTime frame
Fever. Timepoint: 1 MONTH, 2 MONTH, SIX MONTH AFTER TREATMENT. Method of measurement: by thermometer and patient report.;Body pain. Timepoint: 1 MONTH, 2 MONTH, SIX MONTH AFTER TREATMENT. Method of measurement: patient report.;DIAPHORESIS. Timepoint: 1 MONTH, 2 MONTH, SIX MONTH AFTER TREATMENT. Method of measurement: patient report.;Diaphoresis. Timepoint: 1 MONTH, 2 MONTH, SIX MONTH AFTER TREATMENT. Method of measurement: patient report.;ESR. Timepoint: 1 MONTH, 2 MONTH, SIX MONTH AFTER TREATMENT. Method of measurement: by laborator.;CRP. Timepoint: 1 MONTH, 2 MONTH, SIX MONTH AFTER TREATMENT. Method of measurement: BY laboratoary.;WRIGHT. Timepoint: 1 MONTH, 2 MONTH, SIX MONTH AFTER TREATMENT. Method of measurement: agglutination test.;2ME. Timepoint: 1 MONTH, 2 MONTH, SIX MONTH AFTER TREATMENT. Method of measurement: agglutination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Mohsenpour

Sanandaj University of Medical Sciences

behzadmohsenpour@yahoo.com+98 87 3366 4958

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026