End-stage renal disease. End-stage renal disease
Conditions
Interventions
Intervention 1: First intervention group: dialysis patients receiving 2 pills of pomegranate daily containing 225 mg of pomegranate juice (90 mg of elzagic acid) + 400 units of vitamin E per day. Dura
Sponsors
Shahre-kord University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: People who are willing to participate in the study Hemodialysis patients undergoing hemodialysis 3 times a week for at least 3 months Hemodialysis patients who have no malignancy or severe liver problems or infectious diseases Not taking supplements like vitamin E, or other anti-inflammatory and anti-oxidant supplements will be included in the study for 3 months before the intervention.
Exclusion criteria
Exclusion criteria: People who do not follow the protocol Use supplements other than complementary ones People suffering from infectious diseases, malignancy, or liver disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Malondialdehyde(MDA). Timepoint: A week before and one week after the intervention. Method of measurement: Using the kit and instructions specified in the kit.;Oxidized low-density lipoprotein(Ox_LDL). Timepoint: A week before and one week after the intervention. Method of measurement: Using the kit and instructions specified in the kit.;CRP. Timepoint: Before and after 8-week intervention. Method of measurement: ELISA kit according to the protocol.;Interleukin 6. Timepoint: Before and after 8-week intervention. Method of measurement: ELISA kit.;TNF-alpha. Timepoint: Before and after 8-week intervention. Method of measurement: ELISA kit.;Intercellular adhesion molecule 1. Timepoint: before and after 8 week intervention. Method of measurement: ELISA kit.;Vascular cell adhesion molecule 1. Timepoint: before and after 8 week intervention. Method of measurement: ELISA kit.;P-selectin. Timepoint: before and after 8 week intervention. Method of measurement: ELISA kit.;FBS. Timepoint: Before and after 8-week intervention. Method of measurement: enzymatic methods.;?Serum cholesterol. Timepoint: Before and after 8-week intervention. Method of measurement: Enzymatic methods. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: A week before and one week after the intervention. Method of measurement: Quality of Life is a standard and valid questionnaire for determining the quality of life, and is the most commonly recommended method in this area.;Serum triglycerid. Timepoint: Before and after 8-week intervention. Method of measurement: Enzymatic method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTina Jafari
Shahre-kord University of Medical Sciences
Outcome results
None listed