Propofol and Midazolam Effects on Agitation Prevention after Isoflurane Anesthesia in Children Candidate of Surgery

Comparison of Post-anesthetic Administration of Propofol and Midazolam in Prevention of Post-extubation Agitation after Isoflurane Anesthesia in Children undergoing Tonsillectomy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180811040764N1

Enrollment

Registered

2018-08-20

Start date

2018-08-08

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tonsillitis. Chronic diseases of tonsils and adenoids

Interventions

Intervention 1: Intervention group (1): Immediately before termination of isoflurane administration, midazolam with 0.03 mg/kg dosage is administered, Intervention group (2): Immediately before termin

Eligibility

Sex/Gender

All

Age

3 Years to 15 Years

Inclusion criteria

Inclusion criteria: Children aged 3 to 15 years old American Society of Anesthesiologists (ASA) classification I, II Obtaining written consent form from parent

Exclusion criteria

Exclusion criteria: Children with cognition diseases Children with delayed growth factors

Design outcomes

Primary

Measure	Time frame
Agitation level. Timepoint: 5, 10, 20 and 30 minutes after injection medication. Method of measurement: Pediatric Anesthesia Emergence Delirium (PAED) Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoome Mahdavi Rad

Ahvaz University of Medical Sciences

Masi.mahdavi2015@gmail.com+98 61329235893

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026