Melasma..
Conditions
Interventions
Intervention 1: Intervention group: Patients, mounthly, undergo microneedling treatment with a concentration of 4 mg / ml of Tranexamic acid with Amiaemed, with a penetration depth of 1-1 / 2mm. Inte
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: All Women with Melasma.
Exclusion criteria
Exclusion criteria: Coagulopathy Disease. Hormone Therapy. Topical treatment, like Hydroquinone, in the past year. Active Herpes. Facial Wart. Hypersensivity to Tranexamic acid & Hydroquinone. Pregnancy and Lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma intensity based on MASI (Melasma Area Severity Index ) score. Timepoint: (Melasma Area Severity Index ) MASI Score measurement at the beginning of the study and weeks 4, 8,12. Method of measurement: Using the Melasma Area Severity Index (MASI) Score.;The rate of recovery of melasma lesions based on the Patient Global Assessment. Timepoint: The rate of improvement of melasma lesions at the end of the study was based on the Patient Global Assessment questionnaire. Method of measurement: Patient Global Assessment Questionnaire.;The rate of recovery of melasma lesions based on the Patient Global Assessment. Timepoint: The rate of improvement of melasma lesions at the end of the study was based on the Physician Global Assessment questionnaire. Method of measurement: Physician Global Assessment Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHossein Mozayyeni
Kerman University of Medical Sciences
Outcome results
None listed