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Effect of hemp seed oil on clinical symptoms in patients with Knee osteoarthritis referred to the Rheumatology Clinic of Rafsanjan in 2022: A randomized, double-blind, control trial

Effect of hemp seed oil on clinical symptoms in patients with Knee osteoarthritis referred to the Rheumatology Clinic of Rafsanjan in 2022: A randomized, double-blind, control trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180811040759N2
Enrollment
90
Registered
2022-04-05
Start date
2022-04-21
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: Group 1 (30 people) will use Cannabis oil. The treatment duration is 2 months, massage 3 to 5 minutes daily. During the study, patients are only allowed to use ora

Sponsors

Rafsanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age of 45-70 years The diagnosis of osteoarthritis of the knee according to the criteria of the American College of Rheumatology, which is confirmed by a specialist in hematology The presence of moderate knee pain within 24 hours based on linear-visual pain scale (VAS) between 4 7 cm Completing the informed consent form

Exclusion criteria

Exclusion criteria: Patients with inflammatory diseases (such as lupus, rheumatoid arthritis, history of brucellosis, etc.) Cancer or chronic diseases Symptoms or history of liver or kidney failure Oral corticosteroid consumption during the past 4 weeks Corticosteroid injection in the last 6 months fever Consumption of medical herbs continuously Smoking and drug abuse Allergy to hemp seed oil Observe any side effects that the patient thinks are caused by the oil use of food and drug supplements Oral use of other analgesics regularly and advanced disease Use of other topical medications at the site of drug administration Skin or infectious disease or ulcers at the site of pregnancy medication Reluctance to continue participating in the study Failure to comply with the study protocol

Design outcomes

Primary

MeasureTime frame
Knee pain intensity. Timepoint: At the beginning and the end of the study (two months after the beginning of the study). Method of measurement: Visual Analogue Scale (VAS) And WOMAC index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mitra Abbasifard

Rafsanjan University of Medical Sciences

dr.mabbasifard@rums.ac.ir+98 34 3428 0185

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026