Osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group: Group A is used topically in the pyroxicam gel. The treatment duration is 3 months and twice daily. During the study, patients are only allowed to use oral analgesi
Sponsors
Rafsanjan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: age 45-70 years diagnosis of knee osteoarthritis according to American College of Rheumatology, approved by rheumatology specialist the average knee pain within 24 hours is based on the linear-visual pain scale (VAS) between 4 to 7
Exclusion criteria
Exclusion criteria: Patients with inflammatory diseases (such as lupus, rheumatoid arthritis, history of brucellosis, etc.) cancer or chronic diseases symptoms or history of liver or kidney failure oral corticosteroid consumption during the past 4 weeks corticosteroid injection in the last 6 months fever Consumption of medical herbs continuously Smoking pistachio allergy use of food and drug supplements Oral use of other analgesics and other compounds effective in treating osteoarthritis up to 10 days before the study Skin or infectious disease or ulcer at the place of administration pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee pain intensity. Timepoint: At the beginning and the end of the study (three months after the beginning of the study). Method of measurement: The linear-visual scale of pain.;Morning stiffness & Patients' function. Timepoint: At the beginning and the end of the study (three months after the beginning of the study). Method of measurement: WOMAC questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFateme nazhadkoorki
Rafsanjan University of Medical Sciences
Outcome results
None listed