The effect of Probiotics in the prevention of diarrhea caused by antibiotics

Comparison of the effect of probiotics on the prevention of diarrhea in two groups of patients treated with antibiotics and patients treated with antibiotics and probiotics

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180805040711N1

Enrollment

300

Registered

2018-09-15

Start date

2017-04-04

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diarrhea caused by antibiotics. Functional diarrhea

Interventions

Intervention 1: Intervention group: The Probiotic drug capsule containing Saccharomyces cerevisiae brand Yomogi 250 mg. Intervention 2: Control group: 250 mg of lactose-free dry milk will be used in c

Eligibility

Sex/Gender

All

Age

18 Years to 94 Years

Inclusion criteria

Inclusion criteria: The age range is 18-94 years Need to get antibiotics for any cause Conscious Consciousness of Patients to Participate in the Study

Exclusion criteria

Exclusion criteria: Patients with diarrhea at the time of admission Patients with any pathological illness that causes diarrhea History of intestinal surgery Rheumatism and endocarditis Patients treated with laxative Patients who have had antibiotic use in the last 2 weeks Patients with artificial valve and immune deficiency

Design outcomes

Primary

Measure	Time frame
The volume and frequency of antibiotic-induced diarrhea. Timepoint: The beginning of the treatment (before the intervention), during and two weeks after treatment. Method of measurement: Checklist designed in the study (The frequency of diarrhea is over 3 times and the volume of diarrhea is about 200 grams per day).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Seyed Mehdi Haghdoost

Tabriz University of Medical Sciences

haghdustm@tbzmed.ac.ir+98 41 3334 1249

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026