obesity. Obesity due to excess calories
Conditions
Interventions
Intervention 1: Intervention group: 8 week beta glucan supplementation. Intervention 2: Control group: 8-week 7grams of maltodextrin daily.
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
6 Years to 17 Years
Inclusion criteria
Inclusion criteria: Children and adolescents aged 6 to 17 overweight, body mass index score in the range of positive one to positive two standard deviations compared to the standard median determined for age and sex by the World Health Organization for children or adolescents between 5-19 A person with obesity with a body mass index higher than positive 2 standard deviations compared to the standard median determined for age and gender by the World Health Organization for children or adolescents between 5-19 years old Willingness to participate in the study
Exclusion criteria
Exclusion criteria: taking any drugs or supplements that affect the metabolism and mechanisms of blood sugar and insulin, lipid profile and liver enzymes, such as metformin for more than 3 days in the last 1 month Participation in other weight loss programs in the previous 3 months and weight fluctuations of more than 5 kg in the last 2 months. Not suffering from any type of renal, cardiovascular, thyroid, liver and digestive metabolic diseases. Not suffering from secondary obesity such as Cushing's syndrome, obesity, hypogonadal hypothyroidism or hypophysis. Current use of more corticosteroid drugsFrom 5 days in a month. history of surgery in the last 3 months, history of bariatric surgery) Use of drugs to treat psychosis or Manic depression such as lithium, carbamazepine, or Valproic acid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: Digital scales.;Body mass index. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: calculation.;Waist circumference. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: tape measure.;Body mass index Z-score. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: Measurement. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting serum glucose concentration. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: Colorimeter/ laboratory kit.;Fasting serum insulin concentration. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: enzyme-linked immunosorbent assay/laboratory kit.;Total serum cholesterol level. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: Colorimeter/ laboratory kit.;Serum triglyceride level. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: Colorimeter/ laboratory kit.;Serum Low density lipoprotein level. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: Blood biochemical test / colorimetry.;Serum high density lipoprotein level. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: Blood biochemical test / colorimetry.;Alanine amino transferase enzyme. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: photometry.;Aspartate amino transferase. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: photometry.;Gamma glutamyl transferase enzyme. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: Enzymatic colorimetry.;HOMA-IR index. Timepoint: At the beginning and end of the study (2 months after starting the intervention). Method of measurement: formula. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Amani Farani
Shahid Beheshti University of Medical Sciences
Outcome results
None listed