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The effect of metoprolol on reducing mortality in septic patients

Comparison of the Effectiveness of the metoprolol in mortality rate reduction in septic patients admitted to ICU ward

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180804040695N2
Enrollment
36
Registered
2022-02-20
Start date
2022-03-21
Completion date
Unknown
Last updated
2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis. other sepsis

Interventions

Intervention 1: Intervention group: Receiving routine treatment of sepsis in addition to receiving 25 mg oral metoprolol tablets of Alborz Drug Company every eight hours for seven days with regular co

Sponsors

Zanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: over 18 y admitted in the ICU wards of Ayatollah Mousavi Hospital in Zanjan Diagnosis of sepsis less than forty-eight hours after diagnosis

Exclusion criteria

Exclusion criteria: Pregnancy Acute heart failure AV block bradycardia (heart rate below 70 beats per minute) heart shock hypotension (systolic pressure below 90 mm Hg) pulmonary edema sick sinus syndrome ventricular dysfunction acute bronchospasm asthma bronchitis Chronic Obstructive Pulmonary Disease (COPD) Emphysema Pulmonary Disease Peripheral Artery Disease Raynaud's Phenomenon Vasospastic Angina Brest feeding Pheochromocytoma Myasthenia Gravis Liver Diseases

Design outcomes

Primary

MeasureTime frame
Mortality rate of septic patients. Timepoint: Two weeks after the start of the intervention. Method of measurement: Refer to the medical file.;Heart rate. Timepoint: Every six hours until the end of a week. Method of measurement: cardiac monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Zeraati

Zanjan University of Medical Sciences

mohammadrezazeraati@zums.ac.ir+98 24 3313 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026