All patients have long-term ventilation with the same Apache screw.
Conditions
Interventions
Intervention 1: Intervention group: ????? ???? ???Nandrolone intramuscular injection twice a day for one week. Intervention 2: Control group: Injection drug.
Sponsors
Zanjan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patient with long-term separation of mechanical ventilation (over SBT 3 or 7 days from the first SBT to 3 weeks) separate inspiration weakness (caused by myopathy or neuropathy caused by respiratory muscles for any reason). Age 20 to 70 years Sepsis or febrile illness that causes a kind of neuropathy. Lack of lung disease (such as nano-pulmonary pleural effusion-respiratory failure-pulmonary mass and COPD) Patients with the same nutrition or gavage Length of stay in ICU less than 21 days. No electrolyte imbalance NIF having> 30-
Exclusion criteria
Exclusion criteria: Reintubation Patient death before ICU clearance NPO becoming patient during examination Incidence of pulmonary edema, ARDS, pleural effusion and ventilator pneumonia Electrolyte disturbances (hypokalemia, etc.) at any time during the study. Dissatisfaction with the patient's companions Contraindication for the injection of nandrolone such as CHF, recent history of IHD or MI, obstructive europoplasty (BPH) in men, hematocrit over 50 (erythrocytosis), and chronic kidney and liver disease (Increase LFT)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facilitate separation of ventilators in patients with long-term mechanical ventilation. Timepoint: In 3 stages, 3, 5 and 7 per week, variables such as static capacity, R.S.R.I, I.W.I, CORP Index. Method of measurement: Questionnaire (Static Compliace, R.S.R.I, I.W.I, CORP Index). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Reza Zeraati
Zanjan University of Medical Sciences
Outcome results
None listed