Acute ischemic stroke. Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
Conditions
Interventions
Intervention 1: Intervention group: The intervention group will receive 80mg of Curcumin pearl everyday for 8 weeks accompanied with acute ischemic stroke treatments. The first dose will be administer
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age between 50-80 years First ever stroke patients Ischemic stroke GCS<13 NIHSS=4-25 MRS<2 before the stroke Stroke occurrence within prior 12 hours.
Exclusion criteria
Exclusion criteria: Fever at first presentation Presence of other inflammatory conditions Immunosuppressive drug consumption Death within the first week of the study Presence of bedsore during follow-up Occurrence of myocardial infarction during the study follow-up Pregnancy TIA 3 month prior to study Massive brain infarction Declining to participate History of allergy to Turmeric Advanced hepatic conditions malabsorption syndrome History of diabetes Receiving rTPA Mechanical thrombectomy during the study follow-up Presence of dementia Craniotomy during the study follow-up BMI more than 35 Cigarette smoking Alcohol consumption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stroke severity. Timepoint: before intervention, 4 days, 8 weeks and 3 month after intervention. Method of measurement: using NIHSS.;Degree of disability/dependence. Timepoint: before intervention, 4 days, 8 weeks and 3 month after intervention. Method of measurement: using MRS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Activities of Daily Living. Timepoint: before intervention, 4 days, 8 weeks and 3 month after intervention. Method of measurement: Barthel index.;Seizure. Timepoint: before intervention, 4 days, 8 weeks and 3 month after intervention. Method of measurement: according to clinical presentations. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFariborz Rezaeitalab
Mashhad University of Medical Sciences
Outcome results
None listed