Effect of Corticosteroid in Lumbar Spinal Canal Stenosis

Investigating The Effects of Short Term Oral Corticosteroid Treatment in Patients with Acquired Lumbar Canal Stenosis.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180729040636N1

Enrollment

100

Registered

2019-01-14

Start date

2019-01-18

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acquired Lumbar Spinal Canal stenosis. Spinal stenosis, lumbar region

Interventions

Intervention 1: Intervention Group: Prednisolone 10 mg per day for one week, Meloxicam 7.5 mg per day, Vitamin E 400 IU and Pantoprazole 20 mg for 20 days. Intervention 2: Control Group: Meloxicam 7.5

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Written Consent to Enter Study Age Over 18 Years Acquired Lumbar Spinal Canal Stenosis No History of Corticosteroid Susceptibility

Exclusion criteria

Exclusion criteria: Concomitant With Other Systemic Diseases, Such as Blood pressure, Diabetes, BMI>30 kg/m2, Gastroesophageal reflux disease, dyspepsia, renal failure, neuromuscular disorders History of Corticosteroid Use in The Last Three Months. Needing spinal surgery for Acquired Spinal Canal Stenosis Recent infection within 3 months ago or hospital admission for the same reasons Incidence of drug complications/severe allergic reaction to oral corticosteroid history of any surgery on the spine history of gastrointestinal bleeding

Design outcomes

Primary

Measure	Time frame
Walking Distance. Timepoint: Before the Intervention and 2 Months Later. Method of measurement: Metre.;Oswestry Disability Index from Oswestry Low Back Pain questionnaire. Timepoint: Before the Intervention and 2 Months Later. Method of measurement: OSWESTRY LOW BACK PAIN SCORE QUESTIONNAIRE.	—

Secondary

Measure	Time frame
Severity of pain. Timepoint: Before the Intervention and 2 Months Later. Method of measurement: PAIN Numerical Rating Scale.;Low Back Pain. Timepoint: Before the Intervention and 2 Months Later. Method of measurement: Check List.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Akbariaghdam

Esfahan University of Medical Sciences

Akbariaghdam@med.mui.ac.ir+98 31 3620 2085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026