effect of periodontal treatment on IL-17 and IL-23

Effects of Non-Surgical Treatment on Interleukin-17 and Interleukin-23 level in Gingival Crevicular Fluid in patients with periodontitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180729040623N1

Enrollment

Registered

2018-08-16

Start date

2013-10-01

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Chronic periodontitis. Condition 2: Aggressive periodontitis. Chronic periodontitis Aggressive periodontitis

Interventions

Intervention group: All subjects participating in the study are subject to scaling and root-planning treatment, The same people are in control group before the intervention. So there is only one inte

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: systematically healthy individuals with chronic or aggressive periodontitis

Exclusion criteria

Exclusion criteria: history of periodontal treatment within the previous six months, , use of any antibiotics /or immunosuppressive drugs in the past 3 months consumption of any kind of medicine which affects periodontium (including medicine which cause gingival enlargement). pregnancy smoking any immunosuppressive,metabolic or systemic disease

Design outcomes

Primary

Measure	Time frame
Interleukin-17 level. Timepoint: before scaling and root-planning and 6 weeks after intervention. Method of measurement: ELISA test.;Interleukin-23 level. Timepoint: before scaling and root-planning and 6 weeks after intervention. Method of measurement: ELISA test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFereshteh Shanei

Shahed University

fr.shanei@gmail.com+98 21 8895 9210

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026