Pediatric migraine. Migraine
Conditions
Interventions
Intervention group: Cinnarizine(37.5 mg for children 4-11 years of age and 50 mg for children 12-16 years of age, once daily) and Propranolol (1 mg /kg body weight, once daily). Duration of treatment
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
6 Years to 14 Years
Inclusion criteria
Inclusion criteria: Every child with a diagnosis of migraine (according to international headache society) There must be at least 4 episodes of migraine attacks per month. The age range of 6 to 14 years. A migraine headache with or without aura. The patient has not used any drug for preventing migraine headaches during last month Parents agreement and sign informed written consent form.
Exclusion criteria
Exclusion criteria: The patient affected by other forms of migraine headache (variant migraine). The patient has focal neurologic signs or radiologic findings in brain imaging. There is a serious comorbidity. There are other systemic diseases. Inability to participate in the study. Use of drugs for preventing attacks during last month A contraindication to use of cinnarizine or propranolol (such as asthma or heart block).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of migraine headaches. Timepoint: Before intervention and 2,4,8 weeks after intervention. Method of measurement: Frequency of headaches will be recorded daily by the parents in a timetable.;Severity of migraine headaches. Timepoint: Before intervention and 2,4,8 weeks after intervention. Method of measurement: Severity of headaches will be measured by Visual Analog Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactPegah Katibeh
Shiraz University of Medical Sciences
Outcome results
None listed