Effect of dexmedetomine on delirium

Effect of perioperative dexmedetomidine infusion on post operative delirium in on pump heart surgery patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180724040575N4

Enrollment

Registered

2020-10-05

Start date

2019-03-21

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium. Delirium due to known physiological condition

Interventions

Intervention 1: Intervention group: In this group, after induction of anesthesia, dex medetomidine at a dose of 0.2 to 0.5 micrograms per kilogram per hour is started as an intravenous infusion and co

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Adults candidate for cardiac surgery Ejection Fraction(EF) >20%

Exclusion criteria

Exclusion criteria: Known allergy to dexmedetomidine Taking preoperative antipsychotic drugs Lack of patient cooperation and satisfaction History of delirium, neuropsychiatric disorders and seizures Emergency operation

Design outcomes

Primary

Measure	Time frame
Delirium score based on Richmond Agitation Sedation Scale. Timepoint: Evaluation of delirium based on Richmond score before , 6 and 24 h after surgery. Method of measurement: Richmond Agitation Sedation Scale (RASS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKamal Fani

Shahid Beheshti University of Medical Sciences

kamalfani@sbmu.ac.ir+98 21 2207 4095

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026