Effect of tranexamic acid on coronary perfusion

Comparison of different doses of tranexamic acid on coronary perfusion in patients undergoing coronary artery bypass graft surgery (CABG)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180724040575N3

Enrollment

120

Registered

2020-09-29

Start date

2018-08-23

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery bypass graft surgery.

Interventions

Intervention 1: Intervention group: Patients undergoing coronary artery bypass graft receiving a high dose of tranexamic acid. In this group, after induction of anesthesia, tranexamic acid drug made b

Eligibility

Sex/Gender

All

Age

40 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients under CABG surgery Ejection Fraction(EF) >40%

Exclusion criteria

Exclusion criteria: Tranexamic acid sensitivity Convulsion history Thromboembolic event history

Design outcomes

Primary

Measure	Time frame
Cardiac enzymes. Timepoint: Before and 24 hours after surgery. Method of measurement: Eliza method for cardiac enzymes measurment.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKamal Fani

Shahid Beheshti University of Medical Sciences

kamalfani@sbmu.ac.ir+98 21 2207 4089

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026