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Effects of different doses of Naloxone on postoperative hyperparathyroidism

Study of the effect of different doses of Naloxone on postoperative hyperalgesia in patients receiving high-dose RemiFentanyl in hysterectomy surgeries

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180723040570N5
Enrollment
30
Registered
2020-06-27
Start date
2020-07-21
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysterectomy. Prolapse of vaginal vault after hysterectomy

Interventions

Intervention 1: Intervention group 1: Naloxone infusion with a dose of 0.05 µg / kg / min will be arranged by the completion of the surgery. Naloxone is produced by "Tolid daro" company of Iran. Inter

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients candidate for hysterectomy ?ASA 1&2 No drug allergy

Exclusion criteria

Exclusion criteria: Addiction ???Alcohol consumption

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale. Timepoint: 30 minutes before surgery and 1, 2 , 8 and 24 hours after surgery. Method of measurement: Patient's answer.;Ramsy score. Timepoint: 30 minutes before surgery and 1, 2 , 8 and 24 hours after surgery. Method of measurement: Patient's answer.;Pinprick test. Timepoint: 30 minutes before surgery and 1, 2 , 8 and 24 hours after surgery. Method of measurement: Patient's answer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasim Nikoubakht

Iran University of Medical Sciences

Nikoobakht.n@iums.ac.ir+98 21 64351

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026