Effects of Addition parasetamol to morphine, fentanyl and dexmetomidine infusion after surgery to control postoperative pain after orthopedic surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180723040570N3

Enrollment

180

Registered

2019-11-12

Start date

2019-03-21

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

orthopedic surgery.

Interventions

Intervention 1: control group: paracetamol is pumped to the pump at 33 mg /kg/h for 24 hours and fentanyle 0.5 macro/kg/h and resuspended in normal saline to 100 cc. Intervention 2: intervention group

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patient with lower extremity fracture disese Patient with 18 -70 years old

Exclusion criteria

Exclusion criteria: History of the disease psychiatry History of the heart failure ,liver ,kidney ,lung consciousness abnormalities

Design outcomes

Primary

Measure	Time frame
Post operation pain after orthopedic surgery in lower limbs. Timepoint: Ricovery, 4, 8, 12, 24 hours after surgery. Method of measurement: VAS (visual analogue scale).	—

Secondary

Measure	Time frame
Sedation score. Timepoint: Ricovery, 4, 8, 12, 24 hours after surgery. Method of measurement: Questionare of ramsy score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasim Nikoubakht

Iran University of Medical Sciences

Nikoobakht.n@iums.ac.ir+98 21 6651 5000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026