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The effect of Aloe Vera capsule supplementation on prevention of gastrointestinal disorders

The effect of Aloe Vera capsule supplementation on prevention of gastrointestinal disorders in mechanically ventilated patients.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180723040565N1
Enrollment
36
Registered
2018-10-12
Start date
2018-09-06
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients under mechanical ventilation.

Interventions

Intervention 1: Intervention group: They receive one Aloe Vera capsule produced by Iran-Kashan Baraj Essen Company, before gavage at 9 a.m for 5 days. Intervention 2: Control group: This group does no

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: Undergoing mechanical ventilation in ICU Feeding the patient through the gastric tube Being at the age of 15 years or more Air Conditioning Mode SIMV Having informed consent of patient protector, regarding the patients participation in the research. Air Conditioning Mode SIMV Having informed consent of patient's protector, regarding the patient's participation in the research.

Exclusion criteria

Exclusion criteria: Having any surgery in the digestive system. Having a history of stomach ulcers or duodenal ulcers. Having active bleeding. Having food allergy or allergy to Aloe vera Being Pregnant. Undergoing chemotherapy. Being addict Diagnosis of the doctor to change the type and dosage of the patient's laxative Diagnosis of the doctor to change the patient's ventilation mode Diagnosis of the physician based on changing the dose and type of sedation and salivation drugs Hypothyroidism

Design outcomes

Primary

MeasureTime frame
Percentage of people with constipation. Timepoint: Everyday (9 a.m, 3 p.m, 9 p.m) for 5 days. Method of measurement: stethoscope.;Percentage of people with vomiting. Timepoint: Everyday (9 a.m, 3 p.m, 9 p.m) for 5 days. Method of measurement: Counting the number of gas.;Percentage of people with diarrhea. Timepoint: Everyday (9 a.m, 3 p.m, 9 p.m) for 5 days. Method of measurement: Number of pads consumed.;The percentage of people with a residual stomach volume of more than 150 cc. Timepoint: Everyday (9 a.m, 3 p.m, 9 p.m) for 5 days. Method of measurement: 50cc syringe.;Percentage of people with bloating. Timepoint: Everyday (9 a.m, 3 p.m, 9 p.m) for 5 days. Method of measurement: Strip meter.;Percentage of people with ileus. Timepoint: Everyday(9 a.m, 3 p.m, 9 p.m) for 5 days. Method of measurement: stethoscope.;Percentage of people with reduced intestinal sounds. Timepoint: Everyday (9 a.m, 3 p.m, 9 p.m) for 5 days. Method of measurement: stethoscope.;Percentage of people with hematochezia. Timepoint: Before intervention and after intervention. Method of measurement: Complete blood count (CBC) test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMostafa Rad

Sabzevar University of Medical Sciences

mostafarad633@yahoo.com+98 51 4401 8314

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026