Chemotherapy-induced mucositis. Oral mucositis (ulcerative)
Conditions
Interventions
Intervention 1: Intervention group: The research student, in collaboration with the doctors involved in the project, regularly inspects the internal departments of oncology, and if he sees a qualified
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All adult patients (18 years and older) who refer to the inpatient ward of Seyed Al-Shohada Hospital for their treatment at the scheduled time) and develop oral mucositis during treatment. All adult patients (18 years and older) who undergo bone marrow transplantation in the stem cell transplant department at Omid Hospital and develop oral mucositis during transplantation. Having any severity of oral ulcer according to Common Terminology Criteria for Adverse Events version 4.0 classification Have a maximum performance score of 0-2 based on the Eastern Cooperative Oncology Group performance status classification Patients who are expected to survive for more than three months. Patients who have no history of oral and salivary gland diseases.
Exclusion criteria
Exclusion criteria: Patients who have a known allergy to pentoxifylline or any of the excipients used in the oral formulation. Patients who have participated in another ongoing clinical trial unless at least 4 weeks have elapsed since participating in the previous study. Patients with chronic use of steroids or immunosuppressive drugs. Patients who simultaneously have any acute or chronic progressive inflammatory oral disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mouth dryness. Timepoint: One week. Method of measurement: mouth dryness questionnaire (VAS).;Quality of life. Timepoint: one week. Method of measurement: modified Oral Mucositis Daily Questionnaire (modified OMDQ).;Pain severity. Timepoint: one week. Method of measurement: pain scale questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzadeh Moghaddas
Esfahan University of Medical Sciences
Outcome results
None listed