Cancer-induced cachexia. C80.0
Conditions
Interventions
Intervention group: Herbal combination including Trigonella, Foeniculum, Chichorium, Hornleum, and Glycine provided in Dineh company named General Tonic, one sachet three times a day for four weeks.
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: All adult patients (18 years and older) with advanced solid tumor malignancies (Stage 3-4) who encountered cancer-induced anorexia or weight loss (equal or greater than 5% of the previous weight before cancer diagnosis or within the last two months). Cancer patients with serum creatinine < 2 mg / dl. Cancer patients with serum total bilirubin < 2 mg / dl. Patients haven't had any sign of dysphagia or gastrointestinal obstruction. We have expected patients to be alive at least 3 upcoming months. Patients who have received high doses of megestrol due to cachexia and anorexia simultaneously.
Exclusion criteria
Exclusion criteria: Patients who have undergone major surgery for the last 4 weeks. Patients with a history of thrombophlebitis diseases. Patients who have been taking systemic corticosteroid within the last 4 weeks or concurrently. Patients who have cognitive impairment, psychiatric disorder or brain metastasis leading to cognitive impairment. Patients who have diabetes, uncontrolled blood pressure or advanced heart failure (NYHA 4) Patients who have consumed chronic alcohol. Patients who are pregnant or breast-feeding. Patients with a known hypersensitivity reaction to one of the plants in considered herbal combination
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of herbal combination consists of Trigonella, Foeniculum, Chichorium, Hornleum, and Glycine in the prevention of cancer-induced cachexia/anorexia. Timepoint: Baseline and 4 weeks later. Method of measurement: Edmonton criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: Baseline and four weeks later. Method of measurement: Iranian Version of the EORTC QLQ. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzadeh Moghaddas
Esfahan University of Medical Sciences
Outcome results
None listed