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The Effect of Aerobic Exercise on Patients with Heart Failure

The Effect of Eight Weeks of Continuous and Periodic Aerobic Exercise on some Adhesive Molecules and Inflammatory Indices in Men with Heart Failure

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180721040545N1
Enrollment
42
Registered
2018-08-07
Start date
2018-08-05
Completion date
Unknown
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure. Heart failure

Interventions

Intervention 1: Intervention group1: This group carries out continuous aerobic exercise. Continuous aerobic exercise program (with intensity of 45-70% of maximum heart rate) for 8 weeks (3 sessions p

Sponsors

Islamic Azad University, Neyshabour Branch
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to 60 Years

Inclusion criteria

Inclusion criteria: Men aged 50-60 years old with heart failure grade 1-3 according to New York Heart Association (NYHA) criteria; have a heart power of less than 45% and in terms of physical fitness; have potential for exercises.

Exclusion criteria

Exclusion criteria: Having a history of heart disease less than 5 years old, having regular exercise regularly during the past six months, and performing other exercises along with the exercises during the study period, patient dissatisfaction with continued participation in the study; exacerbation of symptoms of heart failure; cardiac arrhythmias; cardiac ischemia; high blood pressure crisis; neurological problems; orthopedic problems.

Design outcomes

Primary

MeasureTime frame
Serum IL-6 level. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: Serum concentrations of IL-6 (pg/ml), Using high-sensitivity ELISA kits.;Serum TNF-a level. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: Serum concentrations of TNF-a (pg/ml), Using high-sensitivity ELISA kits.;Serum hs-CRP level. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: Serum concentrations of hs-CRP (ml/l), Using high-sensitivity ELISA kits.;Serum ICAM-1 level. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: Serum concentrations of ICAM -1 (ng/ml), Using high-sensitivity ELISA kits.;Serum VCAM-1 level. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: Serum concentrations of VCAM -1 (ng/ml), Using high-sensitivity ELISA kits.;Serum E-selectin level. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: Serum concentrations of E-selectin (ng/ml), Using high-sensitivity ELISA kits.;Serum P-selectin level. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: Serum concentrations of P-selectin (ng/ml), Using high-sensitivity ELISA kits.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLadan Hosseni Abrishami

Islamic Azad University, Neyshabour Branch

ladan.abrishami@gmail.com+98 51 3881 6133

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026