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Effect of Ondansetron in Pain and Nausea

Efficacy of Pre-emptive Ondansetron on Patients' pain, Discomfort and Nausea Associated with NG Tube Insertion

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180717040509N5
Enrollment
46
Registered
2020-10-29
Start date
2018-01-05
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, nausea and discomfort from nasal-gastric tube insertion.

Interventions

Intervention 1: Intervention group: For the intervention group 15 minutes before NG tube placement, 10 mg ondansetron (manufactured by Alawi Pharmaceutical Company) was injected intravenously. Interv

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with NG tube Indication

Exclusion criteria

Exclusion criteria: less than 18 years old Unconsciousness Patients with unstable hemodynamic status (systolic blood pressure less than 90 mmHg) Having a nose bleed Anatomical problems in the nose Traumatic patients Sensitivity to Ondansetron Use of Ondansetron interfering drugs (anticholinergic, digoxin, levodopa, tetracycline) Pregnancy Patients with nausea and vomiting problem NG tube more than twice

Design outcomes

Primary

MeasureTime frame
Pain, nausea and discomfort. Timepoint: Immediately, 30 and 60 minutes after NG tube insertion. Method of measurement: Visual Analgesic Score.

Secondary

MeasureTime frame
Bleeding and vomiting after NG tube insertion. Timepoint: Immediately, 30 and 60 minutes after NG tube placement. Method of measurement: Visual Analgesic Score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Hoseininejad

Mazandaran University of Medical Sciences

drhoseininejad@yahoo.com+98 11 3336 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026