Carcinogenic effect of chlorhexidine mouthwash.
Conditions
Interventions
Intervention group: To evaluate the toxicity of chlorhexidine mouthwash and to diagnose its carcinogenicity, chlorhexidine mouthwash 0/2% 250 ml has been prepared by Najo Company and is supposed to re
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Be in the treatment of phase one gingivitis be between 20-30 years old Have gingivitis
Exclusion criteria
Exclusion criteria: The smoking group includes samples with a history of consumption of more than 5 years and above 20 cigarettes per day that are considered Heavy Smoker criteria for taking certain drugs (such as antiretrovirals, doses containing statins, ..) Drug addiction engaging in high-risk occupations such as the paint industry, etc recent viral illness Undergoing radiotherapy or Less than one year history for radiotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Micronucleus. Timepoint: Before scaling and one week after using chlorhexidine mouthwash. Method of measurement: Cell count with light microscope with 400 magnification.;Karyorrehxis. Timepoint: Before scaling and one week after using chlorhexidine mouthwash. Method of measurement: count with light microscope with 400 magnification.;Karyolysis. Timepoint: Before scaling and one week after using chlorhexidine mouthwash. Method of measurement: count with light microscope with 400 magnification.;Broken egg. Timepoint: Before scaling and one week after using chlorhexidine mouthwash. Method of measurement: count with light microscope with 400 magnification.;Repair index. Timepoint: It is calculated after counting nuclear changes. Method of measurement: Mean karyolysis and karyorexia divided by the mean of micronucleus and Broken ag. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNima Nadaf Pour
Islamic Azad University
Outcome results
None listed