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The effect of Mocozift syrup on the success of arteriovenous fistulas

Evaluation of the effect of Mocozift oral syrup (based on Trachyspermum ammi L) on reducing the failure of arteriovenous fistulas in the first 4 weeks after surgery in End Stage Renal Disease patients (ESRD).

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180712040446N4
Enrollment
160
Registered
2022-04-25
Start date
2022-03-02
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Increased success of arteriovenous fistulas of the wrist. End Stage Renal Dieases

Interventions

Intervention 1: Intervention group: The duration of treatment and follow-up for each patient will be a period of 6 weeks. From 2 weeks before the fistula implantation procedure and up to 2 weeks after

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: ESRD patients who have been diagnosed by a nephrologist as candidates for implantation of an arteriovenous fistula on the wrist (Cimino fistula). Patients whom Cimino fistula is performed for the first time. Patients who blood pressure range is more than 60/100 mm / Hg or less than 145/90 mm/Hg on the day of surgery. Patients older than 18 years

Exclusion criteria

Exclusion criteria: Blood pressure below 100/60 mm/Hg Absence of a suitable vessel (helical vein or arterial atherosclerosis) or artery diameter less than 2 and vein diameter less than 2.5 mm Patients who have used anticoagulants. Their vascular system is prepared for Cimino fistula VA and is not suitable for radio cephalic VA. Paralysis or ulceration of the organ where the fistula is to be implanted.

Design outcomes

Primary

MeasureTime frame
Reduction of premature failure of arteriovenous fistulas of the wrist. Timepoint: 6 weeks after surgery. Method of measurement: Observation and examination.;Accelerate the maturation of arteriovenous fistulas. Timepoint: 2 weeks before and 2 weeks after surgery. Method of measurement: Observation and examination.

Secondary

MeasureTime frame
Erythrocyte Sedimentation Rate. Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;Blood Urea Nitrogen (BUN ). Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;C Reactive Protein (CRP). Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;Creatinine (Cr). Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;White Blood Cell Count (WBC). Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;Blood Hemoglobin. Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;Red Blood Cell Distribution Width (RDW). Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;Prothrombin Time (PT). Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;Partial Thromboplastin Time (PTT). Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;International Normalized Ratio (INR). Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.;Ferritin. Timepoint: Before and after the intervention (weeks 0 and 6). Method of measurement: Blood Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohmmad Kamalinejad

Shahid Beheshti University of Medical Sciences

mkamalinejad@yahoo.com+98 21 8820 0118

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026