Vitamin D and Selenium in Type 2 Diabetes

The Effects of Vitamin D and Selenium Supplementation, Alone and in Combination, on Glycemic Indices, Inflammatory Markers, Adipokines, and Metabolic Parameters in Patients with Type 2 Diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180712040438N9

Enrollment

Registered

2024-12-15

Start date

2025-01-19

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus. Type 2 diabetes mellitus

Interventions

Intervention 1: Intervention group: Control group: Intervention group: The Duration of the Intervention will be 3 Months. the Intervention Group will be given one Vitamin D 50,000 IU (anufactured by Z

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Signed informed consent 2. HbA1c above 7% 3. Age between 18 and 75 years 4. Duration of diabetes longer than 1 year 5. Serum vitamin D levels below 30 ng/mL 6. Patients with controlled blood sugar (HbA1c not exceeding 11%) 7. Body Mass Index (BMI) between 25 and 35 kg/m².

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Other autoimmune diseases 3. Hyperglycemia leads to ketoacidosis over the past month 4. Use of insulins 5. Use Supplements Related to the Study

Design outcomes

Primary

Measure	Time frame
Hemoglobin A1c. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;FBS. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Insulin level. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Lipid profiles (TG, TC, LDL-c, HDL-c). Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;PAI-1. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;TPA. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Hs-CRP. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;MDA. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Leptin. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Adiponectin. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Visfastin. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.	—

Measure

Time frame

Hemoglobin A1c. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;FBS. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Insulin level. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Lipid profiles (TG, TC, LDL-c, HDL-c). Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;PAI-1. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;TPA. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Hs-CRP. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;MDA. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Leptin. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Adiponectin. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Visfastin. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.

—

Secondary

Measure	Time frame
Fasting Blood Glucose. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;Total cholesterol. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.;TG. Timepoint: Before and After Intervention. Method of measurement: Biochemical Test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJalal Moludi

Kermanshah University of Medical Sciences

moludij@tbzmed.ac.ir+98 41 3335 2148

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026