Effect of probiotic supplement in treatment of psoriasis

Comparison of the efficacy of probiotic supplement in inflammatory markers, metabolic parameters and some clinical parameters in patients with psoriasis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180712040438N2

Enrollment

Registered

2020-01-10

Start date

2019-08-11

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis. Psoriasis vulgaris

Interventions

Intervention 1: Intervention group: Patients in this group will receive probiotic supplements for 8 weeks. Probiotic supplement is a capsule containing multi-strain probiotic with at least 1.8× 10 9 c

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: diagnosed with psoriasis Subjects aged 15-50 years

Exclusion criteria

Exclusion criteria: patient with chronic renal failure; hemodialysis receiving immunosuppressive, anti-inflammatory and corticosteroid drugs history of supplementation with pre/pro/symbiotic or antioxidants during previous two months

Design outcomes

Primary

Measure	Time frame
Interleukin 6 Level. Timepoint: Baseline and 2 months after intervention. Method of measurement: via ELISA kit.;Interleukin 10 Level. Timepoint: Baseline and 2 months after intervention. Method of measurement: via ELISA kit.;Total cholesterol. Timepoint: Baseline and 2 months after intervention. Method of measurement: spectrophotometry.;Triglycerides. Timepoint: Baseline and 2 months after intervention. Method of measurement: spectrophotometry.;High density lipoprotein. Timepoint: Baseline and 2 months after intervention. Method of measurement: spectrophotometry.;Low density lipoprotein. Timepoint: Baseline and 2 months after intervention. Method of measurement: Formula.;Fasting Blood Sugar. Timepoint: Baseline and 2 months after intervention. Method of measurement: Enzymatic.;Weight. Timepoint: Baseline and 2 months after intervention. Method of measurement: scale.;Body Mass Index. Timepoint: Baseline and 2 months after intervention. Method of measurement: formula.;Hip Circumfrance. Timepoint: Baseline and 2 months after intervention. Method of measurement: meter.;Waist Circumfrance. Timepoint: Baseline and 2 months after intervention. Method of measurement: meter.;Dermatology Life Quality Index (DLQI) score. Timepoint: Baseline and 2 months after intervention. Method of measurement: Dermatology Life Quality Index questionnaire.;Psoriasis Area Severity Index (PASI) score. Timepoint: Baseline and 2 months after intervention. Method of measurement: Psoriasis Area and Severity Index questionnaire.	—

Measure

Time frame

Interleukin 6 Level. Timepoint: Baseline and 2 months after intervention. Method of measurement: via ELISA kit.;Interleukin 10 Level. Timepoint: Baseline and 2 months after intervention. Method of measurement: via ELISA kit.;Total cholesterol. Timepoint: Baseline and 2 months after intervention. Method of measurement: spectrophotometry.;Triglycerides. Timepoint: Baseline and 2 months after intervention. Method of measurement: spectrophotometry.;High density lipoprotein. Timepoint: Baseline and 2 months after intervention. Method of measurement: spectrophotometry.;Low density lipoprotein. Timepoint: Baseline and 2 months after intervention. Method of measurement: Formula.;Fasting Blood Sugar. Timepoint: Baseline and 2 months after intervention. Method of measurement: Enzymatic.;Weight. Timepoint: Baseline and 2 months after intervention. Method of measurement: scale.;Body Mass Index. Timepoint: Baseline and 2 months after intervention. Method of measurement: formula.;Hip Circumfrance. Timepoint: Baseline and 2 months after intervention. Method of measurement: meter.;Waist Circumfrance. Timepoint: Baseline and 2 months after intervention. Method of measurement: meter.;Dermatology Life Quality Index (DLQI) score. Timepoint: Baseline and 2 months after intervention. Method of measurement: Dermatology Life Quality Index questionnaire.;Psoriasis Area Severity Index (PASI) score. Timepoint: Baseline and 2 months after intervention. Method of measurement: Psoriasis Area and Severity Index questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJalal Moludi

Tabriz University of Medical Sciences

Moludij@tbzmed.ac.ir+98 41 3335 2148

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 21, 2026