Knee osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group: Tactile acuity training and routine physiotherapy treatment. Intervention 2: Control group: Routine physiotherapy treatment.
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients of both sexes aged 50 to 75 years Clinical diagnosis of knee osteoarthritis according to the American College of Rheumatology (ACR) criteria Knee osteoarthritis grade 2 or 3 according to the Kellgren-Lawrence (KL) classification Unilateral or bilateral knee pain and dysfunction Chronic knee pain for more than 3 months Pain intensity 3 to 7 on the NRS Cognitive ability above 23 points based on MMSE Minimum score of 40 on the Central Sensitization Questionnaire Disability level greater than 25 based on the WOMAC index
Exclusion criteria
Exclusion criteria: Any neurological or musculoskeletal disorder affecting lower limb function Knee surgery in the past 6 months Participation in a rehabilitation program in the past 6 months Intra-articular injection in the past 6 months Use of antidepressants, anti-inflammatory drugs, or anti-anxiety drugs in the past 6 months Presence of electrical or metal implants Perception and coordination disorders, or any systemic disease Neurological or orthopedic damage that may affect tactile discrimination in the knee Neurological disease Peripheral neuropathies Persistent pain from other causes Inflammatory disorders of the knee joint Presence of vision or hearing problems Fibromyalgia syndrome Major depressive disorder Acute or chronic infection Epilepsy Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Graphesthesia. Timepoint: Before intervention; After intervention; 4 weeks after intervention. Method of measurement: Identifying the correct number of letters and numbers drawn on the skin.;Two point discrimination. Timepoint: Before intervention; After intervention; 4 weeks after intervention. Method of measurement: Sliding caliper.;Point-to-point sensation. Timepoint: Before intervention; After intervention; 4 weeks after intervention. Method of measurement: Monofilament.;Pain. Timepoint: Before intervention; After intervention; 4 weeks after intervention. Method of measurement: Numerical rating scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Function of descending pain inhibitory system. Timepoint: Before intervention; After intervention; 4 weeks after intervention. Method of measurement: Conditioned pain modulation.;Disability. Timepoint: Before intervention; After intervention; 4 weeks after intervention. Method of measurement: Western Ontario and McMaster index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKatayoon Rezaei
Shiraz University of Medical Sciences
Outcome results
None listed