The effect of probiotic administration on severity of the menopausal symptoms and mental health

The effect of probiotic administration on severity of the menopausal symptoms and mental health of the menopausal women

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180707040370N9

Enrollment

Registered

2023-01-19

Start date

2023-02-20

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severity of the Menopausal Symptoms and Mental health. Menopausal and female climacteric states

Interventions

Intervention 1: Intervention group: Probiotic supplement will be prescribed in the form of Oral Capsule 200 mg, Once a day for 6 weeks. Including Lactobacillus plantarum, Lactobacillus casei, Lactobac

Eligibility

Sex/Gender

Female

Age

45 Years to 55 Years

Inclusion criteria

Inclusion criteria: age between 45-55 not using cigarette or alcohol not having physical or mental diseases not using of relaxation techniques not using of hormonal or herbal therapies at least 1 to 5 years have passed since menopause Having menopause symptoms

Exclusion criteria

Exclusion criteria: irregular use of the drug refuse from continuing to participate in study

Design outcomes

Primary

Measure	Time frame
Severity of menopause symptoms. Timepoint: Before the intervention, 3 and 6 weeks after the intervention. Method of measurement: MRS scale.;Stress. Timepoint: Before the intervention, 3 and 6 weeks after the intervention. Method of measurement: Questionnaire DASS-21.;Anxiety. Timepoint: Before the intervention, 3 and 6 weeks after the intervention. Method of measurement: Questionnaire DASS-21.;Depression. Timepoint: Before the intervention, 3 and 6 weeks after the intervention. Method of measurement: Questionnaire DASS-21.	—

Measure

Time frame

Severity of menopause symptoms. Timepoint: Before the intervention, 3 and 6 weeks after the intervention. Method of measurement: MRS scale.;Stress. Timepoint: Before the intervention, 3 and 6 weeks after the intervention. Method of measurement: Questionnaire DASS-21.;Anxiety. Timepoint: Before the intervention, 3 and 6 weeks after the intervention. Method of measurement: Questionnaire DASS-21.;Depression. Timepoint: Before the intervention, 3 and 6 weeks after the intervention. Method of measurement: Questionnaire DASS-21.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactEnsiyeh Jenabi

Hamedan University of Medical Sciences

en.jenabi@yahoo.com+98 81 3838 0496

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026