The effect Allicin and Silybum Marianum supplementation on some of the antioxidant and oxidative indicators

Comparison of the effect a period of consumption Allicin and Silybum Marianum supplementation with four weeks wrestling selective training on some of the antioxidant and oxidative indicators in trained wrestlers

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180705040351N1

Enrollment

Registered

2018-07-17

Start date

2018-07-23

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

antioxidant and oxidative indicators.

Interventions

Intervention 1: Intervention group: first, 24 hours after blood sampling, the subjects received 3 tablets 300 mg containing 1/1 gram of allicin for one month each day made in Isfahan Pharmaceutical C

Eligibility

Sex/Gender

Male

Age

15 Years to 20 Years

Inclusion criteria

Inclusion criteria: Wrestlers who have had a continuous training record of at least five years. At least one championship title has been gained at the provincial level.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Compare differences in the values of SOD change in different groups. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Spectrophotometer made in USA, centrifuge(hermel z310- germany), The kits and chemicals required will also be supplied by Iran's Navand Salamat Company.;Compare differences in the values of MDA change in different groups. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Spectrophotometer made in USA, Water bath made in Iran, centrifuge(hermel z310- germany), The kits and chemicals required will also be supplied by Iran's Navand Salamat Company.;Compare differences in the values of TAC change in different groups. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Spectrophotometer made in USA, centrifuge(hermel z310- germany), The kits and chemicals required will also be supplied by Iran's Navand Salamat Company.	—

Measure

Time frame

Compare differences in the values of SOD change in different groups. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Spectrophotometer made in USA, centrifuge(hermel z310- germany), The kits and chemicals required will also be supplied by Iran's Navand Salamat Company.;Compare differences in the values of MDA change in different groups. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Spectrophotometer made in USA, Water bath made in Iran, centrifuge(hermel z310- germany), The kits and chemicals required will also be supplied by Iran's Navand Salamat Company.;Compare differences in the values of TAC change in different groups. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Spectrophotometer made in USA, centrifuge(hermel z310- germany), The kits and chemicals required will also be supplied by Iran's Navand Salamat Company.

—

Secondary

Measure	Time frame
Score Muscle soreness. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Borg Pain Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hassani

Islamic Azad University

msv.55.hasani@gmail.com+98 25 3665 2981

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026