Effect of intra-peritoneal Dexamethasone on Nausea and Vomiting

Intraperitoneal dexamethasone: a new method for preventing nausea and vomiting after gynecological laparoscopic surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180702040309N1

Enrollment

Registered

2020-05-14

Start date

2020-05-21

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gynecological laparoscopy.

Interventions

Intervention group: 20 ml normal salin containing dexamethasone (16 mg) were injected into diaphragm and peritoneal cavity after the surgery..

Eligibility

Sex/Gender

Female

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Aged 18 to 70 years old Female gender Class 1 or 2 of American Society of Anesthesiologists Classification Candidates for elective gynecologic laparoscopic surgery

Exclusion criteria

Exclusion criteria: Body mass index (BMI) >30, diabetes or other underlying diseases histories of abdominal surgery or chronic pain consuming antiemetic drugs within 48 hours before surgery history of long-term analgesics therapy Addiction to any kinds of substances allergy to anesthetic drugs and dexamethasone

Design outcomes

Primary

Measure	Time frame
Nausea score. Timepoint: 1, 2, 4, 12, 18, 24 hours after surgery. Method of measurement: No - mild - moderate - severe.;Vomiting score. Timepoint: 1, 2, 4, 12, 18, 24 hours after surgery. Method of measurement: None - 1 time - 2 or 3 times - more than 3 times.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Ghodratipour

Yazd University of Medical Sciences

zahra.ghodratipour@yahoo.com+98 31 3630 8409

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026