Intraoperative Local administration of tranexamic acid effect on haemorrhage

Assessment of intraoperative Local administration of tranexamic acid effect on haemorrhage in patients undergoing open prostatectom

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180625040232N8

Enrollment

140

Registered

2022-03-26

Start date

2022-04-03

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhage following prostatectomy due to enlarged prostate. Enlarged prostate

Interventions

Intervention 1: Intervention group: In the intervention group, 1 gr of tranexamic acid (produced by Caspian company) is diluted in 100 cc of normal saline and injected into the prostate fossa during s

Eligibility

Sex/Gender

Male

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age between 18-80 years Having no coagulopathy Consent to participate in the study

Exclusion criteria

Exclusion criteria: Sensitivity to tranexamic acid History of severe heart problems (high risk, very high risk) based on pre-operative cardiac risk assessment

Design outcomes

Primary

Measure	Time frame
Hemoglobin level. Timepoint: Before surgery and 48 hours after surgery. Method of measurement: Blood test.	—

Secondary

Measure	Time frame
Length of hospital stay. Timepoint: Once, at the discharge time. Method of measurement: patient's file.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaman Farshid

Oroumia University of Medical Sciences

samanf63@gmail.com009833457286

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026