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The effect of BeEAM regimen in transplantation of lymphoma patients

Evaulating the effect of BeEAM(Bendamustine,Etoposide,Cytarabine,Melphalan)regimen as a conditioning regimen for autologous bone marrow transplantation in relapsed lymphoma patients

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180622040187N1
Enrollment
20
Registered
2018-07-29
Start date
2017-03-21
Completion date
Unknown
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lymphoma. Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue

Interventions

Intervention group: These patients with relapsed lymphoma are candidates for autologous bone marrow transplantation after salvage chemotherapy. Before autologous bone marrow transplantation the BeEAM

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: All the lymphoma patients from 18 to 65 years old that are candidate for autologous stem cell transplant

Exclusion criteria

Exclusion criteria: Not enough harvesting of CD34+ cells

Design outcomes

Primary

MeasureTime frame
Complete remission of lymphoma within 6 months of transplantation. Timepoint: Six months after the transplant. Method of measurement: CT scan,measurement of lactate dehydrogenase and erythrocytes sedimentation rate.

Secondary

MeasureTime frame
Hematologic toxicity. Timepoint: During hospitalization in the bone marrow transplantation ward. Method of measurement: Comlete blood count test.;Post transplant mortality. Timepoint: 100 days post transplant. Method of measurement: Physical examination.;The interval between stem cell infusion and transplantation. Timepoint: During hospitalization in transplantation ward. Method of measurement: Complete blood count test.;Non hematologic toxicity. Timepoint: 6months post transplantation. Method of measurement: Physical examination,liver and renal function tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Elaheh Vafaie

Shiraz University of Medical Sciences

vafaie@sums.ac.ir+98 71 3647 4332

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026