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The effect of curcumin on arterial stiffness

The effect of curcumin supplementation on non invasive arterial stiffness indices in metabolic syndrome patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180619040151N2
Enrollment
80
Registered
2018-12-27
Start date
2019-01-21
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

metabolic syndrome.

Interventions

Intervention 1: Intervention group: Receiving a single dose of curcumin (500 mg) for 12 weeks. Patients receive their supplement every four weeks. Supplement should be eaten with food. Intervention 2:

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Willingness to participate in the study and the completion of informed consent form Metabolic syndrome Patients

Exclusion criteria

Exclusion criteria: Curcumin sensitivity Regular use of anti-diabetes drugs, antiplatelet drugs, antioxidant supplements, anti-inflammatory drugs, analgesics Use of multivitamin or herbal supplements at least 3 months before the start of the study Liver disease, autoimmune disease, biliary disease, obstructive disease, diabetes, kidney failure, malignancy, kidney stones, calcium oxalate stones Pregnancy and breastfeeding Drug abuse Smoking hookah or cigarettes

Design outcomes

Primary

MeasureTime frame
Pulse wave velocity. Timepoint: At the beginning and the end of the study. Method of measurement: Sphygmocor xcel.;Central Augmentation Index. Timepoint: At the beginning and the end of the study. Method of measurement: Sphygmocor xcel.;Central Augmentation Index75. Timepoint: At the beginning and the end of the study. Method of measurement: Sphygmocor xcel.;Central augmentation pressure. Timepoint: At the beginning and the end of the study. Method of measurement: Sphygmocor xcel.;Brachial blood pressure. Timepoint: At the beginning and the end of the study. Method of measurement: Sphygmocor xcel.;Central blood pressure. Timepoint: At the beginning and the end of the study. Method of measurement: Sphygmocor xcel.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbdolreza Norouzy

Mashhad University of Medical Sciences

norouzya@mums.ac.ir+98 51 3800 2382

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026