premature ovarian failure. Premature menopause
Conditions
Interventions
Intervention 1: Intervention group includes 15 patients with premature ovarian failure that will be treated by stem cell injection. Intervention 2: Control group: includes 15 patients with premature o
Sponsors
Iranian academic center for education culture and research
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: got married woman normal karyotype FSH more than 20 IU/ml anti mullerian hormone; less than 1 ng/ml spermogram: more than 15 million/ml, normal morphology more than 2%, sperm motility (A+B) morethan 25%anteral follicles: less than 5
Exclusion criteria
Exclusion criteria: thyroid dysfunction immune disorders history of cancer, chemotherapy and radiotherapy infected by hepatitis B,C or HIV severe endometriosis history of ovarian surgery diabetes dysfunction of electrolyte or liver tests psychological problem like depression, high stress an anxiety
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number and diameter of anteral follicles, FSH level, AMH level, ovary volume, menstruation. Timepoint: 3 months, 6 months and one year after cell administration. Method of measurement: sonography, embryologic evaluation, biochemical assays. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSomaieh kazemnejad
Iranian academic center for education culture and research
Outcome results
None listed